1ten

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[[Image:1ten.png|left|200px]]
 
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{{STRUCTURE_1ten| PDB=1ten | SCENE= }}
{{STRUCTURE_1ten| PDB=1ten | SCENE= }}
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===STRUCTURE OF A FIBRONECTIN TYPE III DOMAIN FROM TENASCIN PHASED BY MAD ANALYSIS OF THE SELENOMETHIONYL PROTEIN===
===STRUCTURE OF A FIBRONECTIN TYPE III DOMAIN FROM TENASCIN PHASED BY MAD ANALYSIS OF THE SELENOMETHIONYL PROTEIN===
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{{ABSTRACT_PUBMED_1279805}}
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==Function==
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[[http://www.uniprot.org/uniprot/TENA_HUMAN TENA_HUMAN]] Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6.
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{{ABSTRACT_PUBMED_1279805}}
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==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:001279805</ref><ref group="xtra">PMID:011880627</ref><ref group="xtra">PMID:011917145</ref><ref group="xtra">PMID:012217703</ref><ref group="xtra">PMID:014636602</ref><ref group="xtra">PMID:019113835</ref><references group="xtra"/>
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<ref group="xtra">PMID:001279805</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Aukhil, I.]]
[[Category: Aukhil, I.]]

Revision as of 08:40, 23 April 2014

Template:STRUCTURE 1ten

Contents

STRUCTURE OF A FIBRONECTIN TYPE III DOMAIN FROM TENASCIN PHASED BY MAD ANALYSIS OF THE SELENOMETHIONYL PROTEIN

Template:ABSTRACT PUBMED 1279805

Function

[TENA_HUMAN] Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6.

About this Structure

1ten is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Leahy DJ, Hendrickson WA, Aukhil I, Erickson HP. Structure of a fibronectin type III domain from tenascin phased by MAD analysis of the selenomethionyl protein. Science. 1992 Nov 6;258(5084):987-91. PMID:1279805

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OCA

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