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1a1i

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[[Image:1a1i.png|left|200px]]
 
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{{STRUCTURE_1a1i| PDB=1a1i | SCENE= }}
{{STRUCTURE_1a1i| PDB=1a1i | SCENE= }}
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===RADR (ZIF268 VARIANT) ZINC FINGER-DNA COMPLEX (GCAC SITE)===
===RADR (ZIF268 VARIANT) ZINC FINGER-DNA COMPLEX (GCAC SITE)===
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{{ABSTRACT_PUBMED_9562555}}
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==Function==
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[[http://www.uniprot.org/uniprot/EGR1_MOUSE EGR1_MOUSE]] Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'(EGR-site). Activates the transcription of target genes whose products are required for mitogenesis and differentiation.
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{{ABSTRACT_PUBMED_9562555}}
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==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:009562555</ref><references group="xtra"/>
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<ref group="xtra">PMID:009562555</ref><references group="xtra"/><references/>
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Benson, T E.]]
[[Category: Benson, T E.]]

Revision as of 06:29, 10 April 2014

Template:STRUCTURE 1a1i

Contents

RADR (ZIF268 VARIANT) ZINC FINGER-DNA COMPLEX (GCAC SITE)

Template:ABSTRACT PUBMED 9562555

Function

[EGR1_MOUSE] Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'(EGR-site). Activates the transcription of target genes whose products are required for mitogenesis and differentiation.

About this Structure

1a1i is a 3 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

  • Elrod-Erickson M, Benson TE, Pabo CO. High-resolution structures of variant Zif268-DNA complexes: implications for understanding zinc finger-DNA recognition. Structure. 1998 Apr 15;6(4):451-64. PMID:9562555

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