2ovr
From Proteopedia
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m (Protected "2ovr" [edit=sysop:move=sysop]) |
Revision as of 11:14, 16 November 2011
Structure of the Skp1-Fbw7-CyclinEdegN complex
Template:ABSTRACT PUBMED 17434132
About this Structure
2ovr is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Hao B, Oehlmann S, Sowa ME, Harper JW, Pavletich NP. Structure of a Fbw7-Skp1-cyclin E complex: multisite-phosphorylated substrate recognition by SCF ubiquitin ligases. Mol Cell. 2007 Apr 13;26(1):131-43. PMID:17434132 doi:http://dx.doi.org/10.1016/j.molcel.2007.02.022
- Orlicky S, Tang X, Neduva V, Elowe N, Brown ED, Sicheri F, Tyers M. An allosteric inhibitor of substrate recognition by the SCF(Cdc4) ubiquitin ligase. Nat Biotechnol. 2010 Jul;28(7):733-7. Epub 2010 Jun 27. PMID:20581844 doi:10.1038/nbt.1646
