2ydt

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[[Image:2ydt.png|left|200px]]
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==STRUCTURE OF THE ALPHA-L-ARABINOFURANOSIDASE ARB93A FROM FUSARIUM GRAMINEARUM IN COMPLEXE WITH AN IMINOSUGAR INHIBITOR==
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<StructureSection load='2ydt' size='340' side='right' caption='[[2ydt]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2ydt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Gibberella_zeae Gibberella zeae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YDT OCA]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=AHR:ALPHA-L-ARABINOFURANOSE'>AHR</scene>, <scene name='pdbligand=EDG:1,4-DIDEOXY-1,4-IMINO-L-ARABINITOL'>EDG</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2ydp|2ydp]]</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ydt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ydt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ydt RCSB], [http://www.ebi.ac.uk/pdbsum/2ydt PDBsum]</span></td></tr>
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<table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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As part of continued efforts to understand the mechanisms of 1,5-alpha-l-arabinanases better, some arabinan-like iminosugar oligosaccharides were synthesized. An iminosugar analogue of arabinobiose was found to be a good inhibitor of the arabinanase Arb93A from Fusarium graminearum. Structures were determined for complexes of this inhibitor with wild-type Arb93A and a catalytically inactive mutant.
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alpha-L-Arabinofuranosylated pyrrolidines as arabinanase inhibitors.,Goddard-Borger ED, Carapito R, Jeltsch JM, Phalip V, Stick RV, Varrot A Chem Commun (Camb). 2011 Sep 14;47(34):9684-6. Epub 2011 Jul 20. PMID:21773614<ref>PMID:21773614</ref>
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The line below this paragraph, containing "STRUCTURE_2ydt", creates the "Structure Box" on the page.
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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{{STRUCTURE_2ydt| PDB=2ydt | SCENE= }}
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===STRUCTURE OF THE ALPHA-L-ARABINOFURANOSIDASE ARB93A FROM FUSARIUM GRAMINEARUM IN COMPLEXE WITH AN IMINOSUGAR INHIBITOR===
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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</div>
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== References ==
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_21773614}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 21773614 is the PubMed ID number.
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</StructureSection>
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{{ABSTRACT_PUBMED_21773614}}
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==About this Structure==
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[[2ydt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Gibberella_zeae Gibberella zeae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YDT OCA].
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==Reference==
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<ref group="xtra">PMID:021773614</ref><references group="xtra"/>
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[[Category: Alpha-N-arabinofuranosidase]]
[[Category: Alpha-N-arabinofuranosidase]]
[[Category: Gibberella zeae]]
[[Category: Gibberella zeae]]

Revision as of 07:50, 14 May 2014

STRUCTURE OF THE ALPHA-L-ARABINOFURANOSIDASE ARB93A FROM FUSARIUM GRAMINEARUM IN COMPLEXE WITH AN IMINOSUGAR INHIBITOR

2ydt, resolution 1.60Å

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