1o17

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[[Image:1o17.png|left|200px]]
 
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{{STRUCTURE_1o17| PDB=1o17 | SCENE= }}
{{STRUCTURE_1o17| PDB=1o17 | SCENE= }}
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===ANTHRANILATE PHOSPHORIBOSYL-TRANSFERASE (TRPD)===
===ANTHRANILATE PHOSPHORIBOSYL-TRANSFERASE (TRPD)===
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{{ABSTRACT_PUBMED_12093726}}
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==Function==
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[[http://www.uniprot.org/uniprot/TRPD_SULSO TRPD_SULSO]] Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).<ref>PMID:11298741</ref> <ref>PMID:16714288</ref>
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{{ABSTRACT_PUBMED_12093726}}
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==About this Structure==
==About this Structure==
[[1o17]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1k8e 1k8e]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O17 OCA].
[[1o17]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1k8e 1k8e]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O17 OCA].
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==See Also==
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*[[Phosphoribosyltransferase|Phosphoribosyltransferase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:012093726</ref><references group="xtra"/>
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<ref group="xtra">PMID:012093726</ref><references group="xtra"/><references/>
[[Category: Anthranilate phosphoribosyltransferase]]
[[Category: Anthranilate phosphoribosyltransferase]]
[[Category: Sulfolobus solfataricus]]
[[Category: Sulfolobus solfataricus]]

Revision as of 11:06, 16 April 2014

Template:STRUCTURE 1o17

Contents

ANTHRANILATE PHOSPHORIBOSYL-TRANSFERASE (TRPD)

Template:ABSTRACT PUBMED 12093726

Function

[TRPD_SULSO] Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).[1] [2]

About this Structure

1o17 is a 4 chain structure with sequence from Sulfolobus solfataricus. This structure supersedes the now removed PDB entry 1k8e. Full crystallographic information is available from OCA.

See Also

Reference

  • Mayans O, Ivens A, Nissen LJ, Kirschner K, Wilmanns M. Structural analysis of two enzymes catalysing reverse metabolic reactions implies common ancestry. EMBO J. 2002 Jul 1;21(13):3245-54. PMID:12093726 doi:http://dx.doi.org/10.1093/emboj/cdf298
  1. Ivens A, Mayans O, Szadkowski H, Wilmanns M, Kirschner K. Purification, characterization and crystallization of thermostable anthranilate phosphoribosyltransferase from Sulfolobus solfataricus. Eur J Biochem. 2001 Apr;268(8):2246-52. PMID:11298741
  2. Marino M, Deuss M, Svergun DI, Konarev PV, Sterner R, Mayans O. Structural and mutational analysis of substrate complexation by anthranilate phosphoribosyltransferase from Sulfolobus solfataricus. J Biol Chem. 2006 Jul 28;281(30):21410-21. Epub 2006 May 19. PMID:16714288 doi:10.1074/jbc.M601403200

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