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3rwq

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Revision as of 06:21, 28 December 2011

Image:3rwq.png

Template:STRUCTURE 3rwq

Discovery of a Novel, Potent and Selective Inhibitor of 3-Phosphoinositide Dependent Kinase (PDK1)

Template:ABSTRACT PUBMED 22040023

About this Structure

3rwq is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Murphy ST, Bailey S, Burke BJ, Chappie TA, Ferre R, Greasley S, Hickey MJ, Humphrey J, Kablaoui N, Kath J, Kazmirski S, Kraus M, Kupchinskey S, Li J, Marx MA, Richter D, Tanis SP, Tran K, Vernier W, Alton G, Baxi SM, Ermolieff J, Lingardo L, Xie Z, Yin MJ, Yu XH. Discovery of Novel, Potent and Selective Inhibitors of 3-Phosphoinositide-Dependent Kinase (PDK1). J Med Chem. 2011 Oct 31. PMID:22040023 doi:10.1021/jm201019k

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OCA

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