Alkaline phosphatase
From Proteopedia
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| - | {{STRUCTURE_1elx| PDB=1elx | SIZE=400| SCENE= |right|CAPTION=E. coli alkaline phosphatase with Zn+2, Mg+2 and phosphate ions, [[1elx]] }} | + | {{STRUCTURE_1elx| PDB=1elx | SIZE=400| SCENE= |right|CAPTION=E. coli alkaline phosphatase dimer with Zn+2, Mg+2 and phosphate ions, [[1elx]] }} |
'''Alkaline phosphatase''' (ALP) is an enzyme which removes phosphate from nucleotides, proteins and alkaloids. The enzyme is most effective in alkaline environment. | '''Alkaline phosphatase''' (ALP) is an enzyme which removes phosphate from nucleotides, proteins and alkaloids. The enzyme is most effective in alkaline environment. | ||
Revision as of 12:12, 23 October 2012
Alkaline phosphatase (ALP) is an enzyme which removes phosphate from nucleotides, proteins and alkaloids. The enzyme is most effective in alkaline environment.
3D Structures of alkaline phosphatase
Update November 2011
1alk, 1ed9, 1ed8 – EcALP + Zn + Mg – Eschechia coli
3bdh - EcALP + Mg
1aja, 3bdf, 3bdg – EcALP (mutant)
1ali, 1ajb, 1ajc, 1ajd, 1alj, 1ani, 1anj, 2anh, 1hqa, 1urb, 1hjk, 1khk, 1kh7 - EcALP (mutant) + Zn + Mg
1ura - EcALP (mutant) + Zn
1khn - EcALP (mutant) + Zn
1b8j - EcALP + Zn + Mg + VO4
1kh5 - EcALP (mutant) + Zn + Mg + AlF3
1khj - EcALP (mutant) + Zn + AlF3
1k7h – nsALP + Zn + maleic acid – northern shrimp
1shq - nsALP + Zn + Mg
1zeb - hALP + Zn + Mg – human
1zef - hALP + Zn + Mg + phenylalanine
2glq - hALP + Zn + Mg + Sr
3e2d – ALP + Zn + Mg – Vibrio
3a52 - ALP + Zn + Mg – Shewanella
ALP complexes with phosphate derivative
1khl, 3dyc - EcALP (mutant) + Zn + phosphate
1alh, 3tg0 - EcALP + Zn + phosphate
1y6v - EcALP + Co + phosphate
1y7a - EcALP (mutant) + Co + phosphate
1elx, 1ely, 1elz, 1kh9, 1kh4, 2g9y, 3cmr - EcALP (mutant) + Zn + Mg + phosphate
3dpc - EcALP (mutant) + phosphorylated peptide
2ga3 - EcALP (mutant) + Zn + Mg + phosphothreonine
1ew8 - EcALP + Zn + phosphonoacetic acid + phosphate
1ew9 - EcALP + Zn + Mg + mercaptomethyl phosphonate
1shn - nsALP + Zn + phosphate
1zed - hALP + Zn + Mg + PO3 + nitrophenyl hydrogen methylphosphonate
3mk0, 3mk1 - hALP + Zn + Mg + phosphate + nitrophenol + phosphoserine
3mk2 - hALP + Zn + Mg + phosphoserine
2iuc - AbALP + Zn + Mg + phosphate – Antarctic bacterium
2w5v, 2w5x - AbALP (mutant) + Zn + Mg + phosphoserine
2w5w - AbALP (mutant) + Zn + phosphoserine
2x98 - ALP + Zn + Mg + phosphate – Halobacterium salinarum
