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4a7i

From Proteopedia

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m (Protected "4a7i" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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[[Image:4a7i.jpg|left|200px]]
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The entry 4a7i is ON HOLD until Paper Publication
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{{STRUCTURE_4a7i| PDB=4a7i | SCENE= }}
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Authors: Nazare, M., Matter, H., Will, D.W., Wagner, M., Urmann, M., Czech, J., Schreuder, H., Bauer, A., Ritter, K., Wehner, V.
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===Factor Xa in complex with a potent 2-amino-ethane sulfonamide inhibitor===
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Description: Factor Xa in complex with a potent 2-amino-ethane sulfonamide inhibitor
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{{ABSTRACT_PUBMED_22190348}}
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==About this Structure==
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[[4a7i]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A7I OCA].
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==Reference==
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<ref group="xtra">PMID:022190348</ref><references group="xtra"/>
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[[Category: Coagulation factor Xa]]
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[[Category: Homo sapiens]]
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[[Category: Bauer, A.]]
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[[Category: Czech, J.]]
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[[Category: Matter, H.]]
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[[Category: Nazare, M.]]
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[[Category: Ritter, K.]]
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[[Category: Schreuder, H.]]
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[[Category: Urmann, M.]]
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[[Category: Wagner, M.]]
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[[Category: Wehner, V.]]
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[[Category: Will, D W.]]
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[[Category: Blood coagulation factor]]
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[[Category: Calcium- binding]]
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[[Category: Egf-like domain]]
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[[Category: Gamma-carboxyglutamic acid]]
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[[Category: Glycoprotein]]
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[[Category: Hydrolase]]
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[[Category: Hydroxylation]]
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[[Category: Serine protease]]
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[[Category: Serine proteinase]]

Revision as of 07:23, 1 February 2012

Image:4a7i.jpg

Template:STRUCTURE 4a7i

Factor Xa in complex with a potent 2-amino-ethane sulfonamide inhibitor

Template:ABSTRACT PUBMED 22190348

About this Structure

4a7i is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Nazare M, Matter H, Will DW, Wagner M, Urmann M, Czech J, Schreuder H, Bauer A, Ritter K, Wehner V. Fragment deconstruction of small, potent factor xa inhibitors: exploring the superadditivity energetics of fragment linking in protein-ligand complexes. Angew Chem Int Ed Engl. 2012 Jan 23;51(4):905-11. doi:, 10.1002/anie.201107091. Epub 2011 Dec 21. PMID:22190348 doi:10.1002/anie.201107091

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OCA

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