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1wc7

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(New page: 200px<br /> <applet load="1wc7" size="450" color="white" frame="true" align="right" spinBox="true" caption="1wc7, resolution 2.33&Aring;" /> '''FAB FRAGMENT OF PLP...)
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==About this Structure==
==About this Structure==
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1WC7 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]] with IOD and PP3 as [[http://en.wikipedia.org/wiki/ligands ligands]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1WC7 OCA]].
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1WC7 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]] with IOD and PP3 as [[http://en.wikipedia.org/wiki/ligands ligands]]. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1WC7 OCA]].
==Reference==
==Reference==
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[[Category: transamination]]
[[Category: transamination]]
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Oct 29 15:56:43 2007''
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 08:26:27 2007''

Revision as of 06:21, 30 October 2007


1wc7, resolution 2.33Å

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FAB FRAGMENT OF PLP-DEPENDENT CATALYTIC ANTIBODY 15A9 IN COMPLEX WITH PHOSPHOPYRIDOXYL-L-ALANINE

Overview

The purification, crystallization and structure determination at 2.3 A, resolution of the complex of the pyridoxal-5'-phosphate (PLP) dependent, catalytic antibody 15A9 with a phosphopyridoxyl-L-alanine (PPL-L-alanine), substrate analogue are described. The crystal belongs to space group, P2(1), with two molecules in the asymmetric unit related by, non-crystallographic symmetry. The unit-cell parameters are a = 63.5, b =, 81.7, c = 79.3 A and beta is fortuitously 90 degrees . Refinement of the, structure converged at unacceptably high R factors. Although the, traditional analysis of intensity distribution did not indicate twinning, pseudomerohedral twinning was revealed by a newer test based on local, intensity differences [Padilla & Yeates (2003), Acta Cryst. D59, 1124-1130]. When ... [(full description)]

About this Structure

1WC7 is a [Single protein] structure of sequence from [Mus musculus] with IOD and PP3 as [ligands]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].

Reference

Structure of a pseudomerohedrally twinned monoclinic crystal form of a pyridoxal phosphate-dependent catalytic antibody., Golinelli-Pimpaneau B, Acta Crystallogr D Biol Crystallogr. 2005 Apr;61(Pt 4):472-6. Epub 2005, Mar 24. PMID:15805602

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