3ug2

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'''Unreleased structure'''
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[[Image:3ug2.jpg|left|200px]]
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The entry 3ug2 is ON HOLD until Paper Publication
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{{STRUCTURE_3ug2| PDB=3ug2 | SCENE= }}
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Authors: Parker, L.J., Handa, N., Yoshikawa, S., Kukimoto-Niino, M., Shirouzu, M., Yokoyama, S.
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===Crystal structure of the mutated EGFR kinase domain (G719S/T790M) in complex with gefitinib===
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Description:
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(as it appears on PubMed at http://www.pubmed.gov), where 22349823 is the PubMed ID number.
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{{ABSTRACT_PUBMED_22349823}}
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==About this Structure==
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[[3ug2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UG2 OCA].
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==Reference==
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<ref group="xtra">PMID:022349823</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Receptor protein-tyrosine kinase]]
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[[Category: Handa, N.]]
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[[Category: Kukimoto-Niino, M.]]
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[[Category: Parker, L J.]]
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[[Category: Shirouzu, M.]]
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[[Category: Yokoyama, S.]]
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[[Category: Yoshikawa, S.]]
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[[Category: Atp binding]]
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[[Category: Cell cycle]]
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[[Category: Disease mutation]]
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[[Category: Drug resistance]]
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[[Category: Kinase]]
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[[Category: Phosphorylation]]
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[[Category: Receptor]]
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[[Category: Transferase-transferase inhibitor complex]]
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[[Category: Transmembrane]]
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[[Category: Tyrosine-protein kinase]]

Revision as of 05:45, 8 March 2012

Image:3ug2.jpg

Template:STRUCTURE 3ug2

Crystal structure of the mutated EGFR kinase domain (G719S/T790M) in complex with gefitinib

Template:ABSTRACT PUBMED 22349823

About this Structure

3ug2 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Yoshikawa S, Kukimoto-Niino M, Parker L, Handa N, Terada T, Fujimoto T, Terazawa Y, Wakiyama M, Sato M, Sano S, Kobayashi T, Tanaka T, Chen L, Liu ZJ, Wang BC, Shirouzu M, Kawa S, Semba K, Yamamoto T, Yokoyama S. Structural basis for the altered drug sensitivities of non-small cell lung cancer-associated mutants of human epidermal growth factor receptor. Oncogene. 2012 Feb 20. doi: 10.1038/onc.2012.21. PMID:22349823 doi:10.1038/onc.2012.21

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OCA

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