4a92
From Proteopedia
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| - | + | [[Image:4a92.jpg|left|200px]] | |
| - | The | + | <!-- |
| + | The line below this paragraph, containing "STRUCTURE_4a92", creates the "Structure Box" on the page. | ||
| + | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
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| + | {{STRUCTURE_4a92| PDB=4a92 | SCENE= }} | ||
| - | + | ===Full-length HCV NS3-4A protease-helicase in complex with a macrocyclic protease inhibitor.=== | |
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| + | <!-- | ||
| + | The line below this paragraph, {{ABSTRACT_PUBMED_22160684}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 22160684 is the PubMed ID number. | ||
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| + | {{ABSTRACT_PUBMED_22160684}} | ||
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| + | ==About this Structure== | ||
| + | [[4a92]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A92 OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:022160684</ref><references group="xtra"/> | ||
| + | [[Category: Hepatitis c virus]] | ||
| + | [[Category: Arcy, A D.]] | ||
| + | [[Category: Bodendorf, U.]] | ||
| + | [[Category: Eder, J.]] | ||
| + | [[Category: Raman, P.]] | ||
| + | [[Category: Schiering, N.]] | ||
| + | [[Category: Simic, O.]] | ||
| + | [[Category: Svergun, D I.]] | ||
| + | [[Category: Drug design]] | ||
| + | [[Category: Hydrolase]] | ||
Revision as of 07:26, 28 December 2011
Full-length HCV NS3-4A protease-helicase in complex with a macrocyclic protease inhibitor.
Template:ABSTRACT PUBMED 22160684
About this Structure
4a92 is a 2 chain structure with sequence from Hepatitis c virus. Full crystallographic information is available from OCA.
Reference
- Schiering N, D'Arcy A, Villard F, Simic O, Kamke M, Monnet G, Hassiepen U, Svergun DI, Pulfer R, Eder J, Raman P, Bodendorf U. A macrocyclic HCV NS3/4A protease inhibitor interacts with protease and helicase residues in the complex with its full-length target. Proc Natl Acad Sci U S A. 2011 Dec 12. PMID:22160684 doi:10.1073/pnas.1110534108
