3tjd
From Proteopedia
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Revision as of 08:10, 7 December 2011
co-crystal structure of Jak2 with thienopyridine 19
Template:ABSTRACT PUBMED 22087750
About this Structure
3tjd is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Schenkel LB, Huang X, Cheng A, Deak HL, Doherty E, Emkey R, Gu Y, Gunaydin H, Kim JL, Lee J, Loberg R, Olivieri P, Pistillo J, Tang J, Wan Q, Wang HL, Wang SW, Wells MC, Wu B, Yu V, Liu L, Geuns-Meyer S. Discovery of Potent and Highly Selective Thienopyridine Janus Kinase 2 Inhibitors. J Med Chem. 2011 Nov 16. PMID:22087750 doi:10.1021/jm200911r