M2 protein

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{{STRUCTURE_2kj1| PDB=2kj1 | SIZE=300| SCENE= |right| CAPTION=NMR structure of cytoplasmic domain of M2 protein from influenza B virus, [[2kj1]] }}
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{{STRUCTURE_3c9j| PDB=3c9j | SIZE=400| SCENE= |right| CAPTION=NMR structure of cytoplasmic domain of M2 protein from influenza B virus, [[3c9j]] }}
The '''M2 protein''' (M2) is a proton selective ion channelof the infl;uenza virus. It is activated by low pH. M2 has 3 domains: an ectodomain, transmembrane domain (TM) and a C terminal cytoplasmic domain. Transmembrane domain details at [[Molecular Playground/Influenza A M2 transmembrane domain]].
The '''M2 protein''' (M2) is a proton selective ion channelof the infl;uenza virus. It is activated by low pH. M2 has 3 domains: an ectodomain, transmembrane domain (TM) and a C terminal cytoplasmic domain. Transmembrane domain details at [[Molecular Playground/Influenza A M2 transmembrane domain]].

Revision as of 10:51, 4 December 2011

Template:STRUCTURE 3c9j

The M2 protein (M2) is a proton selective ion channelof the infl;uenza virus. It is activated by low pH. M2 has 3 domains: an ectodomain, transmembrane domain (TM) and a C terminal cytoplasmic domain. Transmembrane domain details at Molecular Playground/Influenza A M2 transmembrane domain.

Contents

3D structures of M2 protein

Updated December 2011

3lbw – IavM2 TM (mutant) – Influenza A virus
3bkd - IavM2 TM
3c9j - IavM2 TM + amantadine
2kqt, 1mp6 - IavM2 TM – NMR
2kix - IbvM2 TM (mutant) – Influenza B virus – NMR
2kj1 – IbvM2 cytoplasmic domain - NMR

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Michal Harel, Alexander Berchansky

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