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3mw1
From Proteopedia
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[[Image:3mw1.png|left|200px]] | [[Image:3mw1.png|left|200px]] | ||
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{{STRUCTURE_3mw1| PDB=3mw1 | SCENE= }} | {{STRUCTURE_3mw1| PDB=3mw1 | SCENE= }} | ||
===p38 kinase Crystal structure in complex with small molecule inhibitor=== | ===p38 kinase Crystal structure in complex with small molecule inhibitor=== | ||
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==See Also== | ==See Also== | ||
| - | *[[Mitogen-activated protein kinase]] | + | *[[Mitogen-activated protein kinase|Mitogen-activated protein kinase]] |
==Reference== | ==Reference== | ||
Revision as of 03:52, 27 July 2012
Contents |
p38 kinase Crystal structure in complex with small molecule inhibitor
Template:ABSTRACT PUBMED 21999461
About this Structure
3mw1 is a 1 chain structure of Mitogen-activated protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Lumeras W, Vidal L, Vidal B, Balague C, Orellana A, Maldonado M, Dominguez M, Segarra V, Caturla F. 1,7-Naphthyridine 1-Oxides as Novel Potent and Selective Inhibitors of p38 Mitogen Activated Protein Kinase. J Med Chem. 2011 Nov 24;54(22):7899-910. Epub 2011 Oct 31. PMID:21999461 doi:10.1021/jm200975u
- Lumeras W, Caturla F, Vidal L, Esteve C, Balague C, Orellana A, Dominguez M, Roca R, Huerta JM, Godessart N, Vidal B. Design, Synthesis, and Structure-Activity Relationships of Aminopyridine N-Oxides, a Novel Scaffold for the Potent and Selective Inhibition of p38 Mitogen Activated Protein Kinase. J Med Chem. 2009 Aug 14. PMID:19678708 doi:10.1021/jm9008604
