3rgb

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[[Image:3rgb.png|left|200px]]
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==Crystal structure of particulate methane monooxygenase from Methylococcus capsulatus (Bath)==
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<StructureSection load='3rgb' size='340' side='right' caption='[[3rgb]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3rgb]] is a 9 chain structure with sequence from [http://en.wikipedia.org/wiki/Methylococcus_capsulatus Methylococcus capsulatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RGB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RGB FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=CUA:DINUCLEAR+COPPER+ION'>CUA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3chx|3chx]], [[3rfr|3rfr]], [[1yew|1yew]]</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methane_monooxygenase Methane monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.13.25 1.14.13.25] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rgb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rgb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3rgb RCSB], [http://www.ebi.ac.uk/pdbsum/3rgb PDBsum]</span></td></tr>
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<table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Particulate methane monooxygenase (pMMO) is an integral membrane metalloenzyme that oxidizes methane to methanol in methanotrophic bacteria. Previous biochemical and structural studies of pMMO have focused on preparations from Methylococcus capsulatus (Bath) and Methylosinus trichosporium OB3b. A pMMO from a third organism, Methylocystis species strain M, has been isolated and characterized. Both membrane-bound and solubilized Methylocystis sp. strain M pMMO contain approximately 2 copper ions per 100 kDa protomer and exhibit copper-dependent propylene epoxidation activity. Spectroscopic data indicate that Methylocystis sp. strain M pMMO contains a mixture of Cu(I) and Cu(II), of which the latter exhibits two distinct type 2 Cu(II) electron paramagnetic resonance (EPR) signals. Extended X-ray absorption fine structure (EXAFS) data are best fit with a mixture of Cu-O/N and Cu-Cu ligand environments with a Cu-Cu interaction at 2.52-2.64 A. The crystal structure of Methylocystis sp. strain M pMMO was determined to 2.68 A resolution and is the best quality pMMO structure obtained to date. It provides a revised model for the pmoA and pmoC subunits and has led to an improved model of M. capsulatus (Bath) pMMO. In these new structures, the intramembrane zinc/copper binding site has a different coordination environment from that in previous models.
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Crystal Structure and Characterization of Particulate Methane Monooxygenase from Methylocystis species Strain M.,Smith SM, Rawat S, Telser J, Hoffman BM, Stemmler TL, Rosenzweig AC Biochemistry. 2011 Nov 29;50(47):10231-40. Epub 2011 Nov 3. PMID:22013879<ref>PMID:22013879</ref>
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The line below this paragraph, containing "STRUCTURE_3rgb", creates the "Structure Box" on the page.
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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or leave the SCENE parameter empty for the default display.
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{{STRUCTURE_3rgb| PDB=3rgb | SCENE= }}
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===Crystal structure of particulate methane monooxygenase from Methylococcus capsulatus (Bath)===
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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</div>
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== References ==
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_22013879}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 22013879 is the PubMed ID number.
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</StructureSection>
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{{ABSTRACT_PUBMED_22013879}}
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==About this Structure==
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[[3rgb]] is a 9 chain structure with sequence from [http://en.wikipedia.org/wiki/Methylococcus_capsulatus Methylococcus capsulatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RGB OCA].
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==Reference==
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<ref group="xtra">PMID:022013879</ref><references group="xtra"/>
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[[Category: Methane monooxygenase]]
[[Category: Methane monooxygenase]]
[[Category: Methylococcus capsulatus]]
[[Category: Methylococcus capsulatus]]

Revision as of 04:43, 5 June 2014

Crystal structure of particulate methane monooxygenase from Methylococcus capsulatus (Bath)

3rgb, resolution 2.80Å

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