3qsf

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Revision as of 06:57, 18 April 2012

Template:STRUCTURE 3qsf

The first crystal structure of a human telomeric G-quadruplex DNA bound to a metal-containing ligand (a nickel complex)

Template:ABSTRACT PUBMED 22112241

About this Structure

3qsf is a 1 chain structure. Full crystallographic information is available from OCA.

Reference

• Campbell NH, Karim N, Parkinson GN, Gunaratnam M, Petrucci V, Todd AK, Vilar R, Neidle S. Molecular basis of structure-activity relationships between salphen metal complexes and human telomeric DNA quadruplexes. J Med Chem. 2011 Nov 24. PMID:22112241 doi:10.1021/jm201140v