Plasminogen activator inhibitor
From Proteopedia
(New page: {{STRUCTURE_1c5g| PDB=1c5g | SIZE=400| SCENE= |right|CAPTION=Human plasminogen activator inhibitor 1, 1c5g }} '''Plasminogen activator inhibitor''' (PAI) is a serine protease inhib...) |
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{{STRUCTURE_1c5g| PDB=1c5g | SIZE=400| SCENE= |right|CAPTION=Human plasminogen activator inhibitor 1, [[1c5g]] }} | {{STRUCTURE_1c5g| PDB=1c5g | SIZE=400| SCENE= |right|CAPTION=Human plasminogen activator inhibitor 1, [[1c5g]] }} | ||
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== 3D Structures of plasminogen activator inhibitor == | == 3D Structures of plasminogen activator inhibitor == | ||
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| + | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
===PAI-1=== | ===PAI-1=== | ||
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[[1b3k]], [[1db2]], [[1dvm]], [[1dvn]], [[3cvm]], [[3eox]], [[3q02]], [[3q03]], [[3r4l]] - hPAI-1 (mutant)<br /> | [[1b3k]], [[1db2]], [[1dvm]], [[1dvn]], [[3cvm]], [[3eox]], [[3q02]], [[3q03]], [[3r4l]] - hPAI-1 (mutant)<br /> | ||
[[1a7c]], [[9pai]] – hPAI-1 (mutant) + polypeptide <br /> | [[1a7c]], [[9pai]] – hPAI-1 (mutant) + polypeptide <br /> | ||
| + | [[4g8r]], [[4g8o]] – hPAI-1 + inactivator<br /> | ||
| + | [[4ic0]] - hPAI-1 (mutant) + gallate<br /> | ||
| + | [[3ut3]] - hPAI-1 (mutant) + inhibitor<br /> | ||
| + | [[3aqh]] - hPAI-1 + inhibitor<br /> | ||
[[1oc0]] - hPAI-1 (mutant) + vitronectin<br /> | [[1oc0]] - hPAI-1 (mutant) + vitronectin<br /> | ||
[[3pb1]] - hPAI-1 (mutant) + urokinase (mutant)<br /> | [[3pb1]] - hPAI-1 (mutant) + urokinase (mutant)<br /> | ||
| - | [[3lw2]] – PAI-1 - mouse | + | [[3lw2]] – PAI-1 - mouse<br /> |
| + | [[4kds]] – PAI-1 – trout<br /> | ||
| + | [[4dte]] – PAI-1 – zebra fish<br /> | ||
===PAI-2=== | ===PAI-2=== | ||
Revision as of 09:15, 9 April 2014
Plasminogen activator inhibitor (PAI) is a serine protease inhibitor. PAI-1 inhibits tissue plasminogen activator and urokinase. PAI-2 is secreted by the placenta and is present during pregnancy. PAI-3 inhibits enzymes in blood coagulation.
3D Structures of plasminogen activator inhibitor
Updated on 09-April-2014
PAI-1
1c5g, 1lj5 - hPAI-1 – human
1b3k, 1db2, 1dvm, 1dvn, 3cvm, 3eox, 3q02, 3q03, 3r4l - hPAI-1 (mutant)
1a7c, 9pai – hPAI-1 (mutant) + polypeptide
4g8r, 4g8o – hPAI-1 + inactivator
4ic0 - hPAI-1 (mutant) + gallate
3ut3 - hPAI-1 (mutant) + inhibitor
3aqh - hPAI-1 + inhibitor
1oc0 - hPAI-1 (mutant) + vitronectin
3pb1 - hPAI-1 (mutant) + urokinase (mutant)
3lw2 – PAI-1 - mouse
4kds – PAI-1 – trout
4dte – PAI-1 – zebra fish
PAI-2
1by7 - hPAI-2 (mutant)
1jrr, 2arq, 2arr - hPAI-2 (mutant) + polypeptide
PAI-3
2ol2 – hPAI-3
2hi9 - hPAI-3 residues 25-387
1lq8, 3dy0 – hPAI-3 cleaved
