3sl6
From Proteopedia
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[[Image:3sl6.png|left|200px]] | [[Image:3sl6.png|left|200px]] | ||
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{{STRUCTURE_3sl6| PDB=3sl6 | SCENE= }} | {{STRUCTURE_3sl6| PDB=3sl6 | SCENE= }} | ||
===Crystal structure of the catalytic domain of PDE4D2 with compound 12c=== | ===Crystal structure of the catalytic domain of PDE4D2 with compound 12c=== | ||
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{{ABSTRACT_PUBMED_22030030}} | {{ABSTRACT_PUBMED_22030030}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[3sl6]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SL6 OCA]. | + | [[3sl6]] is a 4 chain structure of [[Phosphodiesterase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SL6 OCA]. |
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| + | ==See Also== | ||
| + | *[[Phosphodiesterase|Phosphodiesterase]] | ||
==Reference== | ==Reference== | ||
Revision as of 14:01, 25 July 2012
Contents |
Crystal structure of the catalytic domain of PDE4D2 with compound 12c
Template:ABSTRACT PUBMED 22030030
About this Structure
3sl6 is a 4 chain structure of Phosphodiesterase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Nankervis JL, Feil SC, Hancock NC, Zheng Z, Ng HL, Morton CJ, Holien JK, Ho PW, Frazzetto MM, Jennings IG, Manallack DT, Martin TJ, Thompson PE, Parker MW. Thiophene inhibitors of PDE4: Crystal structures show a second binding mode at the catalytic domain of PDE4D2. Bioorg Med Chem Lett. 2011 Dec 1;21(23):7089-93. Epub 2011 Oct 5. PMID:22030030 doi:10.1016/j.bmcl.2011.09.109
