4a9o

(Difference between revisions)

Revision as of 06:32, 8 February 2012

4a9o is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Bamborough P, Diallo H, Goodacre JD, Gordon L, Lewis A, Seal JT, Wilson DM, Woodrow MD, Chung CW. Fragment-based discovery of bromodomain inhibitors part 2: optimization of phenylisoxazole sulfonamides. J Med Chem. 2012 Jan 26;55(2):587-96. Epub 2012 Jan 11. PMID:22136469 doi:10.1021/jm201283q

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-'''Unreleased structure'''
+[[Image:4a9o.jpg|left|200px]]
-The entry 4a9o is ON HOLD
+<!--
+The line below this paragraph, containing "STRUCTURE_4a9o", creates the "Structure Box" on the page.
+You may change the PDB parameter (which sets the PDB file loaded into the applet)
+or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+or leave the SCENE parameter empty for the default display.
+-->
+{{STRUCTURE_4a9o|  PDB=4a9o  |  SCENE=  }}
-Authors: Chung, C., Bamborough, P.
+===N-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH 5 ethyl-3-methyl-4-phenyl-1, 2-oxazole===
-Description: N-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH 5 ethyl-3-methyl-4-phenyl-1, 2-oxazole
+<!--
+The line below this paragraph, {{ABSTRACT_PUBMED_22136469}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 22136469 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_22136469}}
+==About this Structure==
+[[4a9o]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A9O OCA].
+==Reference==
+<ref group="xtra">PMID:022136469</ref><references group="xtra"/>
+[[Category: Homo sapiens]]
+[[Category: Bamborough, P.]]
+[[Category: Chung, C W.]]
+[[Category: Signaling protein-inhibitor complex]]