3u2b

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[[Image:3u2b.jpg|left|200px]]
 
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{{STRUCTURE_3u2b| PDB=3u2b | SCENE= }}
{{STRUCTURE_3u2b| PDB=3u2b | SCENE= }}
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===Structure of the Sox4 HMG domain bound to DNA===
===Structure of the Sox4 HMG domain bound to DNA===
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{{ABSTRACT_PUBMED_22181698}}
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==Function==
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[[http://www.uniprot.org/uniprot/SOX4_MOUSE SOX4_MOUSE]] Transcriptional activator that binds with high affinity to the T-cell enhancer motif 5'-AACAAAG-3' motif.
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(as it appears on PubMed at http://www.pubmed.gov), where 22181698 is the PubMed ID number.
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{{ABSTRACT_PUBMED_22181698}}
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==About this Structure==
==About this Structure==
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[[3u2b]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U2B OCA].
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[[3u2b]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U2B OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:022181698</ref><references group="xtra"/>
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<ref group="xtra">PMID:022181698</ref><references group="xtra"/><references/>
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[[Category: Mus musculus]]
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[[Category: Lk3 transgenic mice]]
[[Category: Jauch, R.]]
[[Category: Jauch, R.]]
[[Category: Kolatkar, P R.]]
[[Category: Kolatkar, P R.]]

Revision as of 14:17, 12 March 2014

Template:STRUCTURE 3u2b

Contents

Structure of the Sox4 HMG domain bound to DNA

Template:ABSTRACT PUBMED 22181698

Function

[SOX4_MOUSE] Transcriptional activator that binds with high affinity to the T-cell enhancer motif 5'-AACAAAG-3' motif.

About this Structure

3u2b is a 3 chain structure with sequence from Lk3 transgenic mice. Full crystallographic information is available from OCA.

Reference

  • Jauch R, Ng CK, Narasimhan K, Kolatkar PR. Crystal structure of the Sox4 HMG/DNA complex suggests a mechanism for the positional interdependence in DNA recognition. Biochem J. 2011 Dec 19. PMID:22181698 doi:10.1042/BJ20111768

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