2l9i

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[[Image:2l9i.jpg|left|200px]]
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==NMR structure of thymosin alpha-1==
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<StructureSection load='2l9i' size='340' side='right' caption='[[2l9i]], [[NMR_Ensembles_of_Models | 21 NMR models]]' scene=''>
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== Structural highlights ==
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[[2l9i]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L9I OCA]. <br>
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<b>Activity:</b> <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span><br>
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== Publication Abstract from PubMed ==
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800MHz NMR structure of the 28-residue peptide thymosin alpha-1 in 40% TFE/60% water (v/v) has been determined. Restrained molecular dynamic simulations with an explicit solvent box containing 40% TFE/60% TIP3P water (v/v) were used, in order to get the 3D model of the NMR structure. We found that the peptide adopts a structured conformation having two stable regions: an alpha-helix region from residues 14 to 26 and two double beta-turns in the N-terminal twelve residues which form a distorted helical structure.
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NMR structure of human thymosin alpha-1.,Elizondo-Riojas MA, Chamow SM, Tuthill CW, Gorenstein DG, Volk DE Biochem Biophys Res Commun. 2011 Dec 16;416(3-4):356-61. Epub 2011 Nov 15. PMID:22115779<ref>PMID:22115779</ref>
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The line below this paragraph, containing "STRUCTURE_2l9i", creates the "Structure Box" on the page.
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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or leave the SCENE parameter empty for the default display.
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{{STRUCTURE_2l9i| PDB=2l9i | SCENE= }}
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===NMR structure of thymosin alpha-1===
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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== References ==
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<references/>
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__TOC__
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The line below this paragraph, {{ABSTRACT_PUBMED_22115779}}, adds the Publication Abstract to the page
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 22115779 is the PubMed ID number.
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{{ABSTRACT_PUBMED_22115779}}
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==About this Structure==
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[[2l9i]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L9I OCA].
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==Reference==
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<ref group="xtra">PMID:022115779</ref><references group="xtra"/>
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[[Category: Elizondo-Riojas, M A.]]
[[Category: Elizondo-Riojas, M A.]]
[[Category: Gorenstein, D G.]]
[[Category: Gorenstein, D G.]]

Revision as of 08:30, 30 April 2014

NMR structure of thymosin alpha-1

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