2vik
From Proteopedia
(New page: 200px<br /> <applet load="2vik" size="450" color="white" frame="true" align="right" spinBox="true" caption="2vik" /> '''REFINED STRUCTURE OF THE ACTIN-SEVERING DOM...) |
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==About this Structure== | ==About this Structure== | ||
| - | 2VIK is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2VIK OCA]]. | + | 2VIK is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]]. Structure known Active Sites: ACT, CA1 and CA2. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2VIK OCA]]. |
==Reference== | ==Reference== | ||
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[[Category: cytoskeletal protein]] | [[Category: cytoskeletal protein]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 08:26:44 2007'' |
Revision as of 06:22, 30 October 2007
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REFINED STRUCTURE OF THE ACTIN-SEVERING DOMAIN VILLIN 14T, DETERMINED BY SOLUTION NMR, MINIMIZED AVERAGE STRUCTURE
Overview
Villin 14T is the amino terminal actin monomer binding domain from the, actin-severing and bundling protein villin. Its structure has been, determined in solution using heteronuclear multidimensional nuclear, magnetic resonance (NMR) spectroscopy (Markus MA, Nakayama T, Matsudaira, P, Wagner G. 1994. Solution structure of villin 14T, a domain conserved, among actin-severing proteins. Protein Science 3:70-81). An additional, nuclear Overhauser effect (NOE) spectroscopy data set, acquired using, improved gradient techniques, and further detailed analysis of existing, data sets, produced an additional 601 NOE restraints for structure, calculations. The overall fold does not change significantly with the, additional NOE restraints but the definition of the structure is improved, as judged by ... [(full description)]
About this Structure
2VIK is a [Single protein] structure of sequence from [Gallus gallus]. Structure known Active Sites: ACT, CA1 and CA2. Full crystallographic information is available from [OCA].
Reference
Refined structure of villin 14T and a detailed comparison with other actin-severing domains., Markus MA, Matsudaira P, Wagner G, Protein Sci. 1997 Jun;6(6):1197-209. PMID:9194180
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