Epidermal growth factor

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{{STRUCTURE_2jl9| PDB=1jl9 | SIZE=400| SCENE= |right|CAPTION=Human epidermal growth factor, [[1jl9]] }}
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{{STRUCTURE_2jl9| PDB=1jl9 | SIZE=400| SCENE= |right|CAPTION=Dimer of the monomeric human epidermal growth factor, [[1jl9]] }}

Revision as of 08:51, 30 October 2012

Template:STRUCTURE 2jl9


Epidermal growth factor (EGF) plays a role in cell growth. It binds to its receptor (EGFR). EGF is regulated by iodine. EGF is part of a family of proteins with similar structure and activity. All EGF family proteins contain a conserved amino acid sequence which includes 3 disulfide bonds. Some details on EGF exon in EGF1.

Contents

3D structures of epidermal growth factor

1egf, 1epg, 1eph, 1epi, 1epj, 3egf – mEGF – mouse – NMR
1a3p – mEGF (mutant) – NMR
1jl9 – hEGF
2kv4 – hEGF - NMR
1gk5, 1p9j – hEGF/transforming growth factor alpha - NMR

Heparin-binding EGF-like growth factor

1xdt – hHB-EGF extracellular domain + diphtheria toxin

EGF-like Cripto protein

2j5h – mCR-EGF residues 96-134 - NMR

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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