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O-GlcNAc transferase
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| - | '''O-GlcNac transferase''' (OGT) catalyzes the addition of N-acetylglucosamine (GlcNAc) to serine or threonine residues by O-glycosylation. For details see [[Human O- | + | '''O-GlcNac transferase''' (OGT) catalyzes the addition of N-acetylglucosamine (GlcNAc) to serine or threonine residues by O-glycosylation. For details see [[Human O-GlcNAc transferase]]. |
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Revision as of 16:03, 13 January 2012
O-GlcNac transferase (OGT) catalyzes the addition of N-acetylglucosamine (GlcNAc) to serine or threonine residues by O-glycosylation. For details see Human O-GlcNAc transferase.
3D structures of O-GlcNAc transferase
1fo8, 1fo9, 1foa - rOGT catalytic domain – rabbit
1w3b – hOGT TPR domain – human
2gak – mOGT – mouse
2j0a, 3otk – mOGT catalytic domain (mutant)
OGT binary complexes
2am3, 2am4 - rOGT catalytic domain + UDP-glucose derivative
2am5 - rOGT catalytic domain + UDP
2j0b - mOGT catalytic domain (mutant) + UDP
2apc - rOGT catalytic domain + UDP-GlcNAc phosphonate
2gam - mOGT + b-D-galactose + N-acetyl-galactosamine
3pe3, 3pe4 – hOGT residues 323-1041 + peptide substrate
2jlb – XcOGT + UDP-GlcNAc phosphonate analog – Xanthomonas campestris
2xgm – XcOGT + alloxan + mesoxalylurea
2xgc - XcOGT + UDP-GlcNAc
2xgs - XcOGT + UDP
1nlm – OGT + UDP-acetylglucosamine – Escherichia coli
3ee5 – hOGT + UDP + NAG + galactose + naphthalene derivative
