2yex

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'''Unreleased structure'''
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[[Image:2yex.jpg|left|200px]]
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The entry 2yex is ON HOLD until Paper Publication
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{{STRUCTURE_2yex| PDB=2yex | SCENE= }}
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Authors: Read, J.A., Breed, J., Haye, H., McCall, E., Vallentine, A., White, A.
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===Synthesis and evaluation of triazolones as checkpoint kinase 1 inhibitors===
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Description: Synthesis and evaluation of triazolones as checkpoint kinase 1 inhibitors
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{{ABSTRACT_PUBMED_22342147}}
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==About this Structure==
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[[2yex]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YEX OCA].
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==Reference==
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<ref group="xtra">PMID:022342147</ref><ref group="xtra">PMID:020673630</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Breed, J.]]
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[[Category: Haye, H.]]
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[[Category: Mccall, E.]]
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[[Category: Read, J A.]]
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[[Category: Vallentine, A.]]
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[[Category: White, A.]]
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[[Category: Cell cycle]]
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[[Category: Chk]]
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[[Category: Transferase]]

Revision as of 06:39, 14 March 2012

Image:2yex.jpg

Template:STRUCTURE 2yex

Synthesis and evaluation of triazolones as checkpoint kinase 1 inhibitors

Template:ABSTRACT PUBMED 22342147

About this Structure

2yex is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Oza V, Ashwell S, Brassil P, Breed J, Ezhuthachan J, Deng C, Grondine M, Horn C, Liu D, Lyne P, Newcombe N, Pass M, Read J, Su M, Toader D, Yu D, Yu Y, Zabludoff S. Synthesis and evaluation of triazolones as checkpoint kinase 1 inhibitors. Bioorg Med Chem Lett. 2012 Mar 15;22(6):2330-7. Epub 2012 Feb 1. PMID:22342147 doi:10.1016/j.bmcl.2012.01.043
  • Oza V, Ashwell S, Brassil P, Breed J, Deng C, Ezhuthachan J, Haye H, Horn C, Janetka J, Lyne P, Newcombe N, Otterbien L, Pass M, Read J, Roswell S, Su M, Toader D, Yu D, Yu Y, Valentine A, Webborn P, White A, Zabludoff S, Zheng X. Discovery of a novel class of triazolones as Checkpoint Kinase inhibitors--hit to lead exploration. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5133-8. Epub 2010 Jul 29. PMID:20673630 doi:10.1016/j.bmcl.2010.07.015

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