1b4k
From Proteopedia
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{{STRUCTURE_1b4k| PDB=1b4k | SCENE= }} | {{STRUCTURE_1b4k| PDB=1b4k | SCENE= }} | ||
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===High resolution crystal structure of a MG2-dependent 5-aminolevulinic acid dehydratase=== | ===High resolution crystal structure of a MG2-dependent 5-aminolevulinic acid dehydratase=== | ||
+ | {{ABSTRACT_PUBMED_10356331}} | ||
- | + | ==Function== | |
- | + | [[http://www.uniprot.org/uniprot/HEM2_PSEAE HEM2_PSEAE]] Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity). | |
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==About this Structure== | ==About this Structure== | ||
- | [[1b4k]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | [[1b4k]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseae Pseae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B4K OCA]. |
==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID:010356331</ref><references group="xtra"/> | + | <ref group="xtra">PMID:010356331</ref><references group="xtra"/><references/> |
[[Category: Porphobilinogen synthase]] | [[Category: Porphobilinogen synthase]] | ||
- | [[Category: | + | [[Category: Pseae]] |
[[Category: Frankenberg, N.]] | [[Category: Frankenberg, N.]] | ||
[[Category: Heinz, D W.]] | [[Category: Heinz, D W.]] |
Revision as of 06:41, 10 April 2014
Contents |
High resolution crystal structure of a MG2-dependent 5-aminolevulinic acid dehydratase
Template:ABSTRACT PUBMED 10356331
Function
[HEM2_PSEAE] Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity).
About this Structure
1b4k is a 2 chain structure with sequence from Pseae. Full crystallographic information is available from OCA.
Reference
- Frankenberg N, Erskine PT, Cooper JB, Shoolingin-Jordan PM, Jahn D, Heinz DW. High resolution crystal structure of a Mg2+-dependent porphobilinogen synthase. J Mol Biol. 1999 Jun 11;289(3):591-602. PMID:10356331 doi:10.1006/jmbi.1999.2808