1b4e
From Proteopedia
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{{STRUCTURE_1b4e| PDB=1b4e | SCENE= }} | {{STRUCTURE_1b4e| PDB=1b4e | SCENE= }} | ||
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===X-ray structure of 5-aminolevulinic acid dehydratase complexed with the inhibitor levulinic acid=== | ===X-ray structure of 5-aminolevulinic acid dehydratase complexed with the inhibitor levulinic acid=== | ||
| + | {{ABSTRACT_PUBMED_10194344}} | ||
| - | + | ==Function== | |
| - | + | [[http://www.uniprot.org/uniprot/HEM2_ECOLI HEM2_ECOLI]] Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen. | |
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==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:010194344</ref><references group="xtra"/> | + | <ref group="xtra">PMID:010194344</ref><references group="xtra"/><references/> |
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
[[Category: Porphobilinogen synthase]] | [[Category: Porphobilinogen synthase]] | ||
Revision as of 06:43, 10 April 2014
Contents |
X-ray structure of 5-aminolevulinic acid dehydratase complexed with the inhibitor levulinic acid
Template:ABSTRACT PUBMED 10194344
Function
[HEM2_ECOLI] Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
About this Structure
1b4e is a 1 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.
Reference
- Erskine PT, Norton E, Cooper JB, Lambert R, Coker A, Lewis G, Spencer P, Sarwar M, Wood SP, Warren MJ, Shoolingin-Jordan PM. X-ray structure of 5-aminolevulinic acid dehydratase from Escherichia coli complexed with the inhibitor levulinic acid at 2.0 A resolution. Biochemistry. 1999 Apr 6;38(14):4266-76. PMID:10194344 doi:10.1021/bi982137w
