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3qlg
From Proteopedia
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| + | {{STRUCTURE_3qlg| PDB=3qlg | SCENE= }} | ||
| - | + | ===Crystal structure of the L317I mutant of the C-src tyrosine kinase domain complexed with dasatinib=== | |
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| + | The line below this paragraph, {{ABSTRACT_PUBMED_17355866}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 17355866 is the PubMed ID number. | ||
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| + | {{ABSTRACT_PUBMED_17355866}} | ||
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| + | ==About this Structure== | ||
| + | [[3qlg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QLG OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:017355866</ref><ref group="xtra">PMID:018940662</ref><references group="xtra"/> | ||
| + | [[Category: Gallus gallus]] | ||
| + | [[Category: Non-specific protein-tyrosine kinase]] | ||
| + | [[Category: Boubeva, R.]] | ||
| + | [[Category: Pernot, L.]] | ||
| + | [[Category: Perozzo, R.]] | ||
| + | [[Category: Scapozza, L.]] | ||
| + | [[Category: C-src l317i mutant]] | ||
| + | [[Category: Dasatinib]] | ||
| + | [[Category: Transferase]] | ||
| + | [[Category: Tyrosine kinase]] | ||
Revision as of 06:36, 8 February 2012
Crystal structure of the L317I mutant of the C-src tyrosine kinase domain complexed with dasatinib
Template:ABSTRACT PUBMED 17355866
About this Structure
3qlg is a 2 chain structure with sequence from Gallus gallus. Full crystallographic information is available from OCA.
Reference
- Seeliger MA, Nagar B, Frank F, Cao X, Henderson MN, Kuriyan J. c-Src binds to the cancer drug imatinib with an inactive Abl/c-Kit conformation and a distributed thermodynamic penalty. Structure. 2007 Mar;15(3):299-311. PMID:17355866 doi:10.1016/j.str.2007.01.015
- Dar AC, Lopez MS, Shokat KM. Small molecule recognition of c-Src via the Imatinib-binding conformation. Chem Biol. 2008 Oct 20;15(10):1015-22. PMID:18940662 doi:10.1016/j.chembiol.2008.09.007
