3v8s

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'''Unreleased structure'''
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[[Image:3v8s.jpg|left|200px]]
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The entry 3v8s is ON HOLD until Paper Publication
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{{STRUCTURE_3v8s| PDB=3v8s | SCENE= }}
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Authors: Martin, M.P., Zhu, J.-Yi., Schonbrunn, E.
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===Human RHO-ASSOCIATED PROTEIN KINASE 1 (ROCK 1) IN COMPLEX WITH INDAZOLE DERIVATIVE (COMPOUND 18)===
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Description: Human RHO-ASSOCIATED PROTEIN KINASE 1 (ROCK 1) IN COMPLEX WITH INDAZOLE DERIVATIVE (COMPOUND 18)
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{{ABSTRACT_PUBMED_22272748}}
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==About this Structure==
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[[3v8s]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V8S OCA].
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==Reference==
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<ref group="xtra">PMID:022272748</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Martin, M P.]]
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[[Category: Schonbrunn, E.]]
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[[Category: Zhu, J Yi.]]
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[[Category: Dimerization]]
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[[Category: Inhibitor]]
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[[Category: Kinase]]
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[[Category: Myosin]]
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[[Category: Transferase]]
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[[Category: Transferase-transferase inhibitor complex]]

Revision as of 06:32, 8 February 2012

Image:3v8s.jpg

Template:STRUCTURE 3v8s

Human RHO-ASSOCIATED PROTEIN KINASE 1 (ROCK 1) IN COMPLEX WITH INDAZOLE DERIVATIVE (COMPOUND 18)

Template:ABSTRACT PUBMED 22272748

About this Structure

3v8s is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Li R, Martin MP, Liu Y, Wang B, Patel RA, Zhu J, Sun N, Pireddu R, Lawrence NJ, Li J, Haura EB, Sung SS, Guida WC, Schonbrunn E, Sebti SM. Fragment-based and Structure-guided Discovery and Optimization of Rho Kinase Inhibitors. J Med Chem. 2012 Jan 24. PMID:22272748 doi:10.1021/jm201289r

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OCA

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