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4dce
From Proteopedia
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| - | + | [[Image:4dce.jpg|left|200px]] | |
| - | The | + | <!-- |
| + | The line below this paragraph, containing "STRUCTURE_4dce", creates the "Structure Box" on the page. | ||
| + | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| + | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| + | or leave the SCENE parameter empty for the default display. | ||
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| + | {{STRUCTURE_4dce| PDB=4dce | SCENE= }} | ||
| - | + | ===Crystal structure of human anaplastic lymphoma kinase in complex with a piperidine-carboxamide inhibitor=== | |
| - | + | ||
| + | <!-- | ||
| + | The line below this paragraph, {{ABSTRACT_PUBMED_22263917}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 22263917 is the PubMed ID number. | ||
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| + | {{ABSTRACT_PUBMED_22263917}} | ||
| + | |||
| + | ==About this Structure== | ||
| + | [[4dce]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DCE OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:022263917</ref><references group="xtra"/> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Receptor protein-tyrosine kinase]] | ||
| + | [[Category: Chen, H.]] | ||
| + | [[Category: Epstein, L F.]] | ||
| + | [[Category: Whittington, D A.]] | ||
| + | [[Category: Eml4-alk]] | ||
| + | [[Category: Inhibitor]] | ||
| + | [[Category: Npm-alk]] | ||
| + | [[Category: Receptor tyrosine kinase]] | ||
| + | [[Category: Transferase-inhibitor complex]] | ||
Revision as of 06:31, 8 February 2012
Crystal structure of human anaplastic lymphoma kinase in complex with a piperidine-carboxamide inhibitor
Template:ABSTRACT PUBMED 22263917
About this Structure
4dce is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Bryan MC, Whittington DA, Doherty EM, Falsey JR, Cheng AC, Emkey R, Brake RL, Lewis RT. Rapid Development of Piperidine Carboxamides as Potent and Selective Anaplastic Lymphoma Kinase Inhibitors. J Med Chem. 2012 Jan 20. PMID:22263917 doi:10.1021/jm201565s
