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3tgg

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Revision as of 07:28, 1 February 2012

Image:3tgg.png

Template:STRUCTURE 3tgg

A novel series of potent and selective PDE5 inhibitor2

Template:ABSTRACT PUBMED 21955943

About this Structure

3tgg is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Hughes RO, Maddux T, Joseph Rogier D, Lu S, Walker JK, Jon Jacobsen E, Rumsey JM, Zheng Y, Macinnes A, Bond BR, Han S. Investigation of the pyrazinones as PDE5 inhibitors: Evaluation of regioisomeric projections into the solvent region. Bioorg Med Chem Lett. 2011 Nov 1;21(21):6348-52. Epub 2011 Aug 31. PMID:21955943 doi:10.1016/j.bmcl.2011.08.106

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OCA

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