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TRAIL
From Proteopedia
(Difference between revisions)
(New page: {{STRUCTURE_1d0g| PDB=1d0g | SIZE=400| SCENE= |right|CAPTION=Human TRAIL complex with extracellular domain of DR5, 1d0g }} '''TRAIL (TNF-related apoptosis-inducing ligand)''' functi...) |
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| - | {{STRUCTURE_1d0g| PDB=1d0g | SIZE=400| SCENE= |right|CAPTION=Human TRAIL complex with extracellular domain | + | {{STRUCTURE_1d0g| PDB=1d0g | SIZE=400| SCENE= |right|CAPTION=Human TRAIL trimer residues 114-281 (grey, light green, yellow) complex with death receptor-5 extracellular domain (dark blue, dark green, olive), Zn+2 (grey) and Cl-1 (green) ions, [[1d0g]] }} |
'''TRAIL (TNF-related apoptosis-inducing ligand)''' functions as a ligand in the process of apoptosis. TRAIL binds to death receptors DR4, DR5, DcR1 and DcR2. For details see [[Molecular Playground/TRAIL]]. | '''TRAIL (TNF-related apoptosis-inducing ligand)''' functions as a ligand in the process of apoptosis. TRAIL binds to death receptors DR4, DR5, DcR1 and DcR2. For details see [[Molecular Playground/TRAIL]]. | ||
Revision as of 11:44, 18 November 2012
TRAIL (TNF-related apoptosis-inducing ligand) functions as a ligand in the process of apoptosis. TRAIL binds to death receptors DR4, DR5, DcR1 and DcR2. For details see Molecular Playground/TRAIL.
Contents |
3D Structures of TRAIL
1drv – hTRAIL + DR5 extracellular domain – human
1d0g - hTRAIL residues 114-281 + DR5 extracellular domain
1dg6 – hTRAIL jelly-roll domain
1d2q - hTRAIL extracellular domain
