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3qbc

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[[Image:3qbc.png|left|200px]]
[[Image:3qbc.png|left|200px]]
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{{STRUCTURE_3qbc| PDB=3qbc | SCENE= }}
{{STRUCTURE_3qbc| PDB=3qbc | SCENE= }}
===Structure and design of a new pterin site inhibitor of S. aureus HPPK===
===Structure and design of a new pterin site inhibitor of S. aureus HPPK===
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{{ABSTRACT_PUBMED_22276115}}
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{{ABSTRACT_PUBMED_20445263}}
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==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:020445263</ref><references group="xtra"/>
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<ref group="xtra">PMID:022276115</ref><ref group="xtra">PMID:020445263</ref><references group="xtra"/>
[[Category: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase]]
[[Category: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase]]
[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]

Revision as of 04:55, 27 June 2012

Template:STRUCTURE 3qbc

Structure and design of a new pterin site inhibitor of S. aureus HPPK

Template:ABSTRACT PUBMED 22276115

About this Structure

3qbc is a 2 chain structure with sequence from Staphylococcus aureus. Full crystallographic information is available from OCA.

Reference

  • Chhabra S, Dolezal O, Collins BM, Newman J, Simpson JS, Macreadie IG, Fernley R, Peat TS, Swarbrick JD. Structure of S. aureus HPPK and the discovery of a new substrate site inhibitor. PLoS One. 2012;7(1):e29444. Epub 2012 Jan 19. PMID:22276115 doi:10.1371/journal.pone.0029444
  • Chhabra S, Newman J, Peat TS, Fernley RT, Caine J, Simpson JS, Swarbrick JD. Crystallization and preliminary X-ray analysis of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase from Staphylococcus aureus. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 May 1;66(Pt, 5):575-8. Epub 2010 Apr 30. PMID:20445263 doi:10.1107/S1744309110010857

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