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3vap

From Proteopedia

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'''Unreleased structure'''
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[[Image:3vap.jpg|left|200px]]
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The entry 3vap is ON HOLD until Paper Publication
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{{STRUCTURE_3vap| PDB=3vap | SCENE= }}
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Authors: Voss, M.E., Rainka, M.P., Fleming, M., Peterson, L.H., Belanger, D.B., Siddiqui, M.A., Hruza, A., Voigt, J., Basso, A.D., Gray, K.
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===Synthesis and SAR Studies of imidazo-[1,2-a]-pyrazine Aurora kinase inhibitors with improved off target kinase selectivity===
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Description: Synthesis and SAR Studies of imidazo-[1,2-a]-pyrazine Aurora kinase inhibitors with improved off target kinase selectivity
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{{ABSTRACT_PUBMED_22503250}}
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==About this Structure==
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[[3vap]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VAP OCA].
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==Reference==
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<ref group="xtra">PMID:022503250</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Basso, A D.]]
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[[Category: Belanger, D B.]]
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[[Category: Fleming, M.]]
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[[Category: Gray, K.]]
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[[Category: Hruza, A.]]
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[[Category: Peterson, L H.]]
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[[Category: Rainka, M P.]]
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[[Category: Siddiqui, M A.]]
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[[Category: Voigt, J.]]
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[[Category: Voss, M E.]]
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[[Category: Cell cycle]]
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[[Category: Inhibitor]]
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[[Category: Kinase]]
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[[Category: Transferase]]
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[[Category: Transferase-transferase inhibitor complex]]

Revision as of 19:17, 2 May 2012

Image:3vap.jpg

Template:STRUCTURE 3vap

Synthesis and SAR Studies of imidazo-[1,2-a]-pyrazine Aurora kinase inhibitors with improved off target kinase selectivity

Template:ABSTRACT PUBMED 22503250

About this Structure

3vap is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Voss ME, Rainka MP, Fleming M, Peterson LH, Belanger DB, Siddiqui MA, Hruza A, Voigt J, Gray K, Basso AD. Synthesis and SAR studies of imidazo-[1,2-a]-pyrazine Aurora kinase inhibitors with improved off-target kinase selectivity. Bioorg Med Chem Lett. 2012 Mar 21. PMID:22503250 doi:10.1016/j.bmcl.2012.03.051

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OCA

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