3sqo
From Proteopedia
(Difference between revisions)
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- | + | [[Image:3sqo.jpg|left|200px]] | |
- | The | + | <!-- |
+ | The line below this paragraph, containing "STRUCTURE_3sqo", creates the "Structure Box" on the page. | ||
+ | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
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+ | {{STRUCTURE_3sqo| PDB=3sqo | SCENE= }} | ||
- | + | ===PCSK9 J16 Fab complex=== | |
- | + | ||
+ | <!-- | ||
+ | The line below this paragraph, {{ABSTRACT_PUBMED_22019884}}, adds the Publication Abstract to the page | ||
+ | (as it appears on PubMed at http://www.pubmed.gov), where 22019884 is the PubMed ID number. | ||
+ | --> | ||
+ | {{ABSTRACT_PUBMED_22019884}} | ||
+ | |||
+ | ==About this Structure== | ||
+ | [[3sqo]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SQO OCA]. | ||
+ | |||
+ | ==Reference== | ||
+ | <ref group="xtra">PMID:022019884</ref><references group="xtra"/> | ||
+ | [[Category: Homo sapiens]] | ||
+ | [[Category: Strop, P.]] | ||
+ | [[Category: Cholesterol regulation]] | ||
+ | [[Category: Hydrolase-immune system complex]] | ||
+ | [[Category: Ldlr]] |
Revision as of 09:09, 16 May 2012
PCSK9 J16 Fab complex
Template:ABSTRACT PUBMED 22019884
About this Structure
3sqo is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Liang H, Chaparro-Riggers J, Strop P, Geng T, Sutton JE, Tsai D, Bai L, Abdiche Y, Dilley J, Yu J, Wu S, Chin SM, Lee NA, Rossi A, Lin JC, Rajpal A, Pons J, Shelton DL. Proprotein convertase substilisin/kexin type 9 antagonism reduces low-density lipoprotein cholesterol in statin-treated hypercholesterolemic nonhuman primates. J Pharmacol Exp Ther. 2012 Feb;340(2):228-36. Epub 2011 Oct 21. PMID:22019884 doi:10.1124/jpet.111.187419