4agm

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m (Protected "4agm" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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[[Image:4agm.jpg|left|200px]]
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The entry 4agm is ON HOLD
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{{STRUCTURE_4agm| PDB=4agm | SCENE= }}
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Authors: Joerger, A.C., Wilcken, R., Boeckler, F.M., Fersht, A.R.
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===Structure of the p53 core domain mutant Y220C bound to the stabilizing small molecule PhiKan5086===
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Description: Structure of the p53 core domain mutant Y220C bound to the stabilizing small molecule PhiKan5086
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{{ABSTRACT_PUBMED_17015838}}
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==About this Structure==
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[[4agm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AGM OCA].
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==Reference==
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<ref group="xtra">PMID:017015838</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Boeckler, F M.]]
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[[Category: Fersht, A R.]]
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[[Category: Joerger, A C.]]
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[[Category: Wilcken, R.]]
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[[Category: Aggregation]]
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[[Category: Apoptosis]]
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[[Category: Cancer mutation]]
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[[Category: Cell cycle]]
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[[Category: Halogen bonding]]
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[[Category: Mutant rescue]]
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[[Category: Protein folding]]
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[[Category: Protein stabilization]]
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[[Category: Small-molecule drug]]
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[[Category: Surface crevice]]
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[[Category: Transcription]]
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[[Category: Zinc binding]]

Revision as of 07:51, 21 March 2012

Image:4agm.jpg

Template:STRUCTURE 4agm

Structure of the p53 core domain mutant Y220C bound to the stabilizing small molecule PhiKan5086

Template:ABSTRACT PUBMED 17015838

About this Structure

4agm is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Joerger AC, Ang HC, Fersht AR. Structural basis for understanding oncogenic p53 mutations and designing rescue drugs. Proc Natl Acad Sci U S A. 2006 Oct 10;103(41):15056-61. Epub 2006 Oct 2. PMID:17015838

Proteopedia Page Contributors and Editors (what is this?)

OCA

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