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4dfu

From Proteopedia

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[[Category: Minasov, G.]]
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[[Category: Stogios, P J.]]
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[[Category: Aminoglycoside phosphotransferase]]
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Revision as of 06:54, 22 February 2012

Image:4dfu.png

Template:STRUCTURE 4dfu

Inhibition of an antibiotic resistance enzyme: crystal structure of aminoglycoside phosphotransferase APH(2")-ID/APH(2")-IVA in complex with kanamycin inhibited with quercetin

Template:ABSTRACT PUBMED 22195561

About this Structure

4dfu is a 2 chain structure with sequence from Enterococcus casseliflavus and Streptomyces kanamyceticus. This structure supersedes the now removed PDB entries and 3r82. Full crystallographic information is available from OCA.

Reference

  • Shakya T, Stogios PJ, Waglechner N, Evdokimova E, Ejim L, Blanchard JE, McArthur AG, Savchenko A, Wright GD. A small molecule discrimination map of the antibiotic resistance kinome. Chem Biol. 2011 Dec 23;18(12):1591-601. PMID:22195561 doi:10.1016/j.chembiol.2011.10.018

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OCA

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