This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3v5q

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:3v5q.jpg|left|200px]]
+
==Discovery of a selective TRK Inhibitor with efficacy in rodent cancer tumor models==
-
 
+
<StructureSection load='3v5q' size='340' side='right' caption='[[3v5q]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
-
<!--
+
== Structural highlights ==
-
The line below this paragraph, containing "STRUCTURE_3v5q", creates the "Structure Box" on the page.
+
<table><tr><td colspan='2'>[[3v5q]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V5Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3V5Q FirstGlance]. <br>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0F4:1-(3-{[(3Z)-2-OXO-3-(1H-PYRROL-2-YLMETHYLIDENE)-2,3-DIHYDRO-1H-INDOL-6-YL]AMINO}PHENYL)-3-[3-(TRIFLUOROMETHYL)PHENYL]UREA'>0F4</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene><br>
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NTRK3, TRKC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
-
or leave the SCENE parameter empty for the default display.
+
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr>
-
-->
+
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3v5q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v5q OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3v5q RCSB], [http://www.ebi.ac.uk/pdbsum/3v5q PDBsum]</span></td></tr>
-
{{STRUCTURE_3v5q| PDB=3v5q | SCENE= }}
+
<table>
-
 
+
__TOC__
-
===Discovery of a selective TRK Inhibitor with efficacy in rodent cancer tumor models===
+
</StructureSection>
-
 
+
-
 
+
-
==About this Structure==
+
-
[[3v5q]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V5Q OCA].
+
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Receptor protein-tyrosine kinase]]

Revision as of 05:43, 5 June 2014

Discovery of a selective TRK Inhibitor with efficacy in rodent cancer tumor models

3v5q, resolution 2.20Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3v5q"
Views
Personal tools
Navigation
Toolbox