4ddl
From Proteopedia
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| - | + | [[Image:4ddl.jpg|left|200px]] | |
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| + | The line below this paragraph, containing "STRUCTURE_4ddl", creates the "Structure Box" on the page. | ||
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| + | {{STRUCTURE_4ddl| PDB=4ddl | SCENE= }} | ||
| - | + | ===PDE10a Crystal Structure Complexed with Novel Inhibitor=== | |
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| + | The line below this paragraph, {{ABSTRACT_PUBMED_22365755}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 22365755 is the PubMed ID number. | ||
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| + | {{ABSTRACT_PUBMED_22365755}} | ||
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| + | ==About this Structure== | ||
| + | [[4ddl]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DDL OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:022365755</ref><references group="xtra"/> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Chmait, S.]] | ||
| + | [[Category: Jordan, S.]] | ||
| + | [[Category: Zhang, J.]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
| + | [[Category: Phosphodiesterase 10a]] | ||
Revision as of 07:30, 21 March 2012
PDE10a Crystal Structure Complexed with Novel Inhibitor
Template:ABSTRACT PUBMED 22365755
About this Structure
4ddl is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Hu E, Kunz RK, Rumfelt S, Chen N, Burli R, Li C, Andrews KL, Zhang J, Chmait S, Kogan J, Lindstrom M, Hitchcock SA, Treanor J. Discovery of potent, selective, and metabolically stable 4-(pyridin-3-yl)cinnolines as novel phosphodiesterase 10A (PDE10A) inhibitors. Bioorg Med Chem Lett. 2012 Mar 15;22(6):2262-5. Epub 2012 Feb 8. PMID:22365755 doi:10.1016/j.bmcl.2012.01.086
