1qbs

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Revision as of 06:47, 22 February 2012

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Template:STRUCTURE 1qbs

Contents 1 HIV-1 PROTEASE INHIBITORS WIIH LOW NANOMOLAR POTENCY 2 About this Structure 3 See Also 4 Reference

HIV-1 PROTEASE INHIBITORS WIIH LOW NANOMOLAR POTENCY

Template:ABSTRACT PUBMED 8784449

About this Structure

1qbs is a 2 chain structure of Virus protease with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

See Also

• Virus protease

Reference

• Lam PY, Ru Y, Jadhav PK, Aldrich PE, DeLucca GV, Eyermann CJ, Chang CH, Emmett G, Holler ER, Daneker WF, Li L, Confalone PN, McHugh RJ, Han Q, Li R, Markwalder JA, Seitz SP, Sharpe TR, Bacheler LT, Rayner MM, Klabe RM, Shum L, Winslow DL, Kornhauser DM, Hodge CN, et al.. Cyclic HIV protease inhibitors: synthesis, conformational analysis, P2/P2' structure-activity relationship, and molecular recognition of cyclic ureas. J Med Chem. 1996 Aug 30;39(18):3514-25. PMID:8784449 doi:10.1021/jm9602571
• Ishima R, Louis JM, Torchia DA. Characterization of two hydrophobic methyl clusters in HIV-1 protease by NMR spin relaxation in solution. J Mol Biol. 2001 Jan 19;305(3):515-21. PMID:11152609 doi:10.1006/jmbi.2000.4321