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3vjm

From Proteopedia

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'''Unreleased structure'''
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[[Image:3vjm.jpg|left|200px]]
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The entry 3vjm is ON HOLD until Paper Publication
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{{STRUCTURE_3vjm| PDB=3vjm | SCENE= }}
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Authors: Akahoshi, F., Kishida, H., Miyaguchi, I., Yoshida, T., Ishii, S.
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===Crystal structure of human depiptidyl peptidase IV (DPP-4) in complex with a prolylthiazolidine inhibitor #1===
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Description: Crystal structure of human depiptidyl peptidase IV (DPP-4) in complex with a prolylthiazolidine inhibitor #1
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{{ABSTRACT_PUBMED_22824762}}
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==About this Structure==
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[[3vjm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VJM OCA].
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==Reference==
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<ref group="xtra">PMID:022824762</ref><references group="xtra"/>
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[[Category: Dipeptidyl-peptidase IV]]
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[[Category: Homo sapiens]]
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[[Category: Akahoshi, F.]]
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[[Category: Ishii, S.]]
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[[Category: Kishida, H.]]
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[[Category: Miyaguchi, I.]]
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[[Category: Yoshida, T.]]
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[[Category: Alpha/beta]]
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[[Category: Aminopeptidase]]
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[[Category: Beta-propeller]]
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[[Category: Cell membrane]]
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[[Category: Diabetes]]
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[[Category: Glycoprotein]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Serine protease]]
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[[Category: Signal-anchor]]
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[[Category: Transmembrane]]

Revision as of 05:46, 15 August 2012

Image:3vjm.jpg

Template:STRUCTURE 3vjm

Crystal structure of human depiptidyl peptidase IV (DPP-4) in complex with a prolylthiazolidine inhibitor #1

Template:ABSTRACT PUBMED 22824762

About this Structure

3vjm is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Yoshida T, Akahoshi F, Sakashita H, Sonda S, Takeuchi M, Tanaka Y, Nabeno M, Kishida H, Miyaguchi I, Hayashi Y. Fused bicyclic heteroarylpiperazine-substituted l-prolylthiazolidines as highly potent DPP-4 inhibitors lacking the electrophilic nitrile group. Bioorg Med Chem. 2012 Aug 15;20(16):5033-41. Epub 2012 Jul 5. PMID:22824762 doi:10.1016/j.bmc.2012.06.033

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OCA

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