3uw4

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[[Image:3uw4.jpg|left|200px]]
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===Crystal structure of cIAP1 BIR3 bound to GDC0152===
===Crystal structure of cIAP1 BIR3 bound to GDC0152===
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The line below this paragraph, {{ABSTRACT_PUBMED_22413863}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 22413863 is the PubMed ID number.
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{{ABSTRACT_PUBMED_22413863}}
==About this Structure==
==About this Structure==
[[3uw4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UW4 OCA].
[[3uw4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UW4 OCA].
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==Reference==
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<ref group="xtra">PMID:022413863</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Hymowitz, S.]]
[[Category: Hymowitz, S.]]

Revision as of 06:58, 28 March 2012

Template:STRUCTURE 3uw4

Crystal structure of cIAP1 BIR3 bound to GDC0152

Template:ABSTRACT PUBMED 22413863

About this Structure

3uw4 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Flygare J, Beresini M, Budha N, Chan H, Chan I, Cheeti S, Cohen F, Deshayes K, Doerner K, Eckhardt G, Elliott LO, Feng B, Franklin M, Reisner S, Gazzard L, Halladay J, Hymowitz SG, La H, Lorusso P, Maurer B, Murray L, Plise E, Quan C, Stephan JP, Young S, Tom J, Tsui V, Um J, Varfolomeev E, Vucic D, Wagner A, Wallweber H, Wang L, Ware J, Wen Z, Wong H, Wong J, Wong M, Wong S, Yu R, Zobel K, Fairbrother WJ. The Discovery of a Potent Small-Molecule Antagonist of Inhibitor of Apoptosis (IAP) Proteins and Clinical Candidate for the Treatment of Cancer (GDC-0152). J Med Chem. 2012 Mar 13. PMID:22413863 doi:10.1021/jm300060k

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