3uw5
From Proteopedia
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===Crystal structure of the BIR domain of MLIAP bound to GDC0152=== | ===Crystal structure of the BIR domain of MLIAP bound to GDC0152=== | ||
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| + | The line below this paragraph, {{ABSTRACT_PUBMED_22413863}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 22413863 is the PubMed ID number. | ||
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| + | {{ABSTRACT_PUBMED_22413863}} | ||
==About this Structure== | ==About this Structure== | ||
[[3uw5]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UW5 OCA]. | [[3uw5]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UW5 OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:022413863</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Hymowitz, S G.]] | [[Category: Hymowitz, S G.]] | ||
Revision as of 06:25, 28 March 2012
Crystal structure of the BIR domain of MLIAP bound to GDC0152
Template:ABSTRACT PUBMED 22413863
About this Structure
3uw5 is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Flygare J, Beresini M, Budha N, Chan H, Chan I, Cheeti S, Cohen F, Deshayes K, Doerner K, Eckhardt G, Elliott LO, Feng B, Franklin M, Reisner S, Gazzard L, Halladay J, Hymowitz SG, La H, Lorusso P, Maurer B, Murray L, Plise E, Quan C, Stephan JP, Young S, Tom J, Tsui V, Um J, Varfolomeev E, Vucic D, Wagner A, Wallweber H, Wang L, Ware J, Wen Z, Wong H, Wong J, Wong M, Wong S, Yu R, Zobel K, Fairbrother WJ. The Discovery of a Potent Small-Molecule Antagonist of Inhibitor of Apoptosis (IAP) Proteins and Clinical Candidate for the Treatment of Cancer (GDC-0152). J Med Chem. 2012 Mar 13. PMID:22413863 doi:10.1021/jm300060k
