4dtk

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-	'''Unreleased structure'''	+	[[Image:4dtk.jpg|left|200px]]
-	The entry 4dtk is ON HOLD until Paper Publication	+	{{STRUCTURE_4dtk| PDB=4dtk | SCENE= }}
-	Authors: Ferguson, A.D.	+	===Novel and selective pan-PIM kinase inhibitor===
-	Description: Novel and selective pan-PIM kinase inhibitor	+	{{ABSTRACT_PUBMED_22727640}}
		+
		+	==About this Structure==
		+	[[4dtk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DTK OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:022727640</ref><references group="xtra"/>
		+	[[Category: Homo sapiens]]
		+	[[Category: Non-specific serine/threonine protein kinase]]
		+	[[Category: Ferguson, A D.]]
		+	[[Category: Kinase]]
		+	[[Category: Pim1]]
		+	[[Category: Transferase-transferase inhibitor complex]]

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Revision as of 08:11, 11 July 2012

Template:STRUCTURE 4dtk

Novel and selective pan-PIM kinase inhibitor

Template:ABSTRACT PUBMED 22727640

About this Structure

4dtk is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

• Dakin LA, Block MH, Chen H, Code E, Dowling JE, Feng X, Ferguson AD, Green I, Hird AW, Howard T, Keeton EK, Lamb ML, Lyne PD, Pollard H, Read J, Wu AJ, Zhang T, Zheng X. Discovery of novel benzylidene-1,3-thiazolidine-2,4-diones as potent and selective inhibitors of the PIM-1, PIM-2, and PIM-3 protein kinases. Bioorg Med Chem Lett. 2012 Jul 15;22(14):4599-604. Epub 2012 Jun 6. PMID:22727640 doi:10.1016/j.bmcl.2012.05.098