3v7t

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'''Unreleased structure'''
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[[Image:3v7t.jpg|left|200px]]
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The entry 3v7t is ON HOLD until Paper Publication
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{{STRUCTURE_3v7t| PDB=3v7t | SCENE= }}
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Authors: Zhang, Y., Colonna, C., Michot, N.
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===Crystal Structure of Human Beta-Tryptase Complexed with a Synthetic Inhibitor with a Tropanylamide Scaffold===
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Description: Crystal Structure of Human Beta-Tryptase Complexed with a Synthetic Inhibitor with a Tropanylamide Scaffold
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{{ABSTRACT_PUBMED_22264487}}
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==About this Structure==
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[[3v7t]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V7T OCA].
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==Reference==
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<ref group="xtra">PMID:022264487</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Colonna, C.]]
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[[Category: Michot, N.]]
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[[Category: Zhang, Y.]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Protein-ligand complex]]
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[[Category: Serine protease]]
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[[Category: Tetramer]]
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[[Category: Tryptase]]

Revision as of 06:35, 14 March 2012

Image:3v7t.jpg

Template:STRUCTURE 3v7t

Crystal Structure of Human Beta-Tryptase Complexed with a Synthetic Inhibitor with a Tropanylamide Scaffold

Template:ABSTRACT PUBMED 22264487

About this Structure

3v7t is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Liang G, Choi-Sledeski YM, Shum P, Chen X, Poli GB, Kumar V, Minnich A, Wang Q, Tsay J, Sides K, Kang J, Zhang Y. A beta-tryptase inhibitor with a tropanylamide scaffold to improve in vitro stability and to lower hERG channel binding affinity. Bioorg Med Chem Lett. 2012 Feb 15;22(4):1606-10. Epub 2012 Jan 3. PMID:22264487 doi:10.1016/j.bmcl.2011.12.127

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OCA

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