4dwv

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m (Protected "4dwv" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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[[Image:4dwv.jpg|left|200px]]
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The entry 4dwv is ON HOLD
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{{STRUCTURE_4dwv| PDB=4dwv | SCENE= }}
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Authors: Plapp, B.V., Ramaswamy, S.
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===Horse alcohol dehydrogenase complexed with NAD+ and 2,3,4,5,6-pentafluorobenzyl alcohol===
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Description: Horse alcohol dehydrogenase complexed with NAD+ and 2,3,4,5,6-pentafluorobenzyl alcohol
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{{ABSTRACT_PUBMED_8172897}}
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==About this Structure==
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[[4dwv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DWV OCA].
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==Reference==
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<ref group="xtra">PMID:008172897</ref><ref group="xtra">PMID:012627956</ref><ref group="xtra">PMID:012855684</ref><references group="xtra"/>
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[[Category: Alcohol dehydrogenase]]
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[[Category: Equus caballus]]
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[[Category: Plapp, B V.]]
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[[Category: Ramaswamy, S.]]
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[[Category: Alcohol dehydrogenase]]
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[[Category: Michaelis complex]]
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[[Category: Nad+]]
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[[Category: Oxidoreductase]]
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[[Category: Pentafluorobenzyl alcohol]]
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[[Category: Rossmann fold]]

Revision as of 07:12, 11 April 2012

Image:4dwv.jpg

Template:STRUCTURE 4dwv

Horse alcohol dehydrogenase complexed with NAD+ and 2,3,4,5,6-pentafluorobenzyl alcohol

Template:ABSTRACT PUBMED 8172897

About this Structure

4dwv is a 2 chain structure with sequence from Equus caballus. Full crystallographic information is available from OCA.

Reference

  • Ramaswamy S, Eklund H, Plapp BV. Structures of horse liver alcohol dehydrogenase complexed with NAD+ and substituted benzyl alcohols. Biochemistry. 1994 May 3;33(17):5230-7. PMID:8172897
  • Rubach JK, Plapp BV. Amino acid residues in the nicotinamide binding site contribute to catalysis by horse liver alcohol dehydrogenase. Biochemistry. 2003 Mar 18;42(10):2907-15. PMID:12627956 doi:10.1021/bi0272656
  • Venkataramaiah TH, Plapp BV. Formamides mimic aldehydes and inhibit liver alcohol dehydrogenases and ethanol metabolism. J Biol Chem. 2003 Sep 19;278(38):36699-706. Epub 2003 Jul 10. PMID:12855684 doi:10.1074/jbc.M305419200

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