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(Difference between revisions)
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==Structure== | ==Structure== | ||
| - | <StructureSection load='1IFA' size='400' align='right' caption='Interferon-β' scene='Sandbox_37/Interferon_beta/1'></StructureSection> | ||
| - | Interferon-β is a relatively simple biological response modifier | + | <Structure load='1IFA' size='400' frame='true' align='center' caption='Interferon-β' scene='Sandbox_37/Interferon_beta/1' /> |
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| + | Interferon-β is a relatively simple biological response modifier, with several <scene name='Sandbox_37/Interferon_beta/2'>identifiable regions</scene>. It consists of five <scene name='Sandbox_37/Ifnb_alpha_helices/1'>alpha helices</scene>, as well as multiple interconnecting <scene name='Sandbox_37/Ifnb_loops/1'>loop regions</scene>. Helices A, B and D run <scene name='Sandbox_37/Ifnb_parallel_abd/1'>parallel to one another</scene>, and helices C and E run <scene name='Sandbox_37/Interferon_beta/3'>anti-parallel</scene> to the other three helices. | ||
<ref name="Structure">PMID:20616576</ref> | <ref name="Structure">PMID:20616576</ref> | ||
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==Inhibition== | ==Inhibition== | ||
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===Inhibitors of Interferon-β=== | ===Inhibitors of Interferon-β=== | ||
===Interferon-β as an Inhibitor=== | ===Interferon-β as an Inhibitor=== | ||
Revision as of 23:46, 13 March 2012
| Please do NOT make changes to this Sandbox. Sandboxes 30-60 are reserved for use by Biochemistry 410 & 412 at Messiah College taught by Dr. Hannah Tims during Fall 2012 and Spring 2013. |
Contents |
Interferon-β
Introduction
History
Structure
|
Interferon-β is a relatively simple biological response modifier, with several . It consists of five , as well as multiple interconnecting . Helices A, B and D run , and helices C and E run to the other three helices. [1]
Solvent Interactions
Mechanism
Inhibition
Inhibitors of Interferon-β
Interferon-β as an Inhibitor
Function
Biochemical
Immunological
References
- ↑ Kudo M. Management of hepatocellular carcinoma: from prevention to molecular targeted therapy. Oncology. 2010 Jul;78 Suppl 1:1-6. Epub 2010 Jul 8. PMID:20616576 doi:10.1159/000315222
- ↑ http://www.uniprot.org/uniprot/P00784
