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1yde
From Proteopedia
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{{STRUCTURE_1yde| PDB=1yde | SCENE= }} | {{STRUCTURE_1yde| PDB=1yde | SCENE= }} | ||
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===Crystal Structure of Human Retinal Short-Chain Dehydrogenase/Reductase 3=== | ===Crystal Structure of Human Retinal Short-Chain Dehydrogenase/Reductase 3=== | ||
| + | {{ABSTRACT_PUBMED_17067289}} | ||
| - | + | ==Function== | |
| - | + | [[http://www.uniprot.org/uniprot/DHR10_HUMAN DHR10_HUMAN]] Has NAD-dependent 17-beta-hydroxysteroid dehydrogenase activity. Converts oestradiol to oestrone. The physiological substrate is not known. Acts on oestradiol and 5-androstene-3-beta,17-beta-diol (in vitro).<ref>PMID:17067289</ref> | |
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==About this Structure== | ==About this Structure== | ||
| - | [[1yde]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | [[1yde]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YDE OCA]. |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:017067289</ref><references group="xtra"/> | + | <ref group="xtra">PMID:017067289</ref><references group="xtra"/><references/> |
| - | [[Category: | + | [[Category: Human]] |
[[Category: Arrowsmith, C.]] | [[Category: Arrowsmith, C.]] | ||
[[Category: Bunkozci, G.]] | [[Category: Bunkozci, G.]] | ||
Revision as of 08:21, 23 April 2014
Contents |
Crystal Structure of Human Retinal Short-Chain Dehydrogenase/Reductase 3
Template:ABSTRACT PUBMED 17067289
Function
[DHR10_HUMAN] Has NAD-dependent 17-beta-hydroxysteroid dehydrogenase activity. Converts oestradiol to oestrone. The physiological substrate is not known. Acts on oestradiol and 5-androstene-3-beta,17-beta-diol (in vitro).[1]
About this Structure
1yde is a 16 chain structure with sequence from Human. Full crystallographic information is available from OCA.
Reference
- Lukacik P, Keller B, Bunkoczi G, Kavanagh KL, Lee WH, Adamski J, Oppermann U. Structural and biochemical characterization of human orphan DHRS10 reveals a novel cytosolic enzyme with steroid dehydrogenase activity. Biochem J. 2007 Mar 15;402(3):419-27. PMID:17067289 doi:BJ20061319
- ↑ Lukacik P, Keller B, Bunkoczi G, Kavanagh KL, Lee WH, Adamski J, Oppermann U. Structural and biochemical characterization of human orphan DHRS10 reveals a novel cytosolic enzyme with steroid dehydrogenase activity. Biochem J. 2007 Mar 15;402(3):419-27. PMID:17067289 doi:BJ20061319
