4alg
From Proteopedia
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| - | + | [[Image:4alg.jpg|left|200px]] | |
| - | + | {{STRUCTURE_4alg| PDB=4alg | SCENE= }} | |
| - | + | ===N-Terminal Bromodomain of Human BRD2 With IBET-151=== | |
| - | + | {{ABSTRACT_PUBMED_22437115}} | |
| + | |||
| + | ==About this Structure== | ||
| + | [[4alg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ALG OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:022437115</ref><references group="xtra"/> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Bouillot, A.]] | ||
| + | [[Category: Chung, C.]] | ||
| + | [[Category: Donche, F.]] | ||
| + | [[Category: Lamotte, Y.]] | ||
| + | [[Category: Mirguet, O.]] | ||
| + | [[Category: Epigenetic reader]] | ||
| + | [[Category: Histone]] | ||
| + | [[Category: Inhibitor]] | ||
| + | [[Category: Signaling protein]] | ||
Revision as of 07:38, 4 July 2012
N-Terminal Bromodomain of Human BRD2 With IBET-151
Template:ABSTRACT PUBMED 22437115
About this Structure
4alg is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Seal J, Lamotte Y, Donche F, Bouillot A, Mirguet O, Gellibert F, Nicodeme E, Krysa G, Kirilovsky J, Beinke S, McCleary S, Rioja I, Bamborough P, Chung CW, Gordon L, Lewis T, Walker AL, Cutler L, Lugo D, Wilson DM, Witherington J, Lee K, Prinjha RK. Identification of a novel series of BET family bromodomain inhibitors: binding mode and profile of I-BET151 (GSK1210151A). Bioorg Med Chem Lett. 2012 Apr 15;22(8):2968-72. Epub 2012 Feb 24. PMID:22437115 doi:10.1016/j.bmcl.2012.02.041
