4alh

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m (Protected "4alh" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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[[Image:4alh.jpg|left|200px]]
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The entry 4alh is ON HOLD
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{{STRUCTURE_4alh| PDB=4alh | SCENE= }}
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Authors: Chung, C.W., Bamborough, P.
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===N-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH 3,5 dimethyl-4-phenyl-1,2- oxazole===
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Description: N-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH 3,5 dimethyl-4-phenyl-1,2-oxazole
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{{ABSTRACT_PUBMED_22136469}}
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==About this Structure==
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[[4alh]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4a9p 4a9p]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ALH OCA].
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==Reference==
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<ref group="xtra">PMID:022136469</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Bamborough, P.]]
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[[Category: Chung, C W.]]
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[[Category: Epigenetic reader]]
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[[Category: Histone]]
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[[Category: Signaling protein-inhibitor complex]]

Revision as of 06:56, 11 April 2012

Template:STRUCTURE 4alh

N-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH 3,5 dimethyl-4-phenyl-1,2- oxazole

Template:ABSTRACT PUBMED 22136469

About this Structure

4alh is a 3 chain structure with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 4a9p. Full crystallographic information is available from OCA.

Reference

  • Bamborough P, Diallo H, Goodacre JD, Gordon L, Lewis A, Seal JT, Wilson DM, Woodrow MD, Chung CW. Fragment-based discovery of bromodomain inhibitors part 2: optimization of phenylisoxazole sulfonamides. J Med Chem. 2012 Jan 26;55(2):587-96. Epub 2012 Jan 11. PMID:22136469 doi:10.1021/jm201283q

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